The Molecular Toxicology speciality section is interested in the molecular mechanisms whereby chemicals cause toxicity. There are several reasons for this interest. Firstly, mechanisms of toxicity can reveal fundamental aspects of biology. Thus, toxins such as cyanide and rotenone were used to reveal the existence of the Krebs cycle, a central component of cellular energy metabolism. Secondly, understanding of mechanisms of toxicity is essential for meaningful extrapolation of results obtained in experimental systems, for the risk assessment of human exposure to chemicals. Thus there are examples where the extrapolation from high dose to low dose requires a non-linear model on the basis of knowledge of a mechanism, and there are examples where extrapolation from species-to-species requires detailed knowledge of mechanisms. Finally, the application of novel molecular biology methods offers fantastic opportunities for enhancing our understanding of toxicology.
The Molecular Toxicology group therefore is committed to embracing a dynamic and expanding vision of the future of toxicology, and is seeking to expand its membership, and the relevance of its mission for the membership of Eurotox. We actively seek engagement with the membership, and a mailing list is available for all those who wish to participate (see: http://tech.groups.yahoo.com/group/EurotoxMoltox/). Anyone whowishes to engage with the group may also contact the chair directly.
The Molecular Toxicology group is also keen to develop the science within Eurotox, and plays an active role in developing the agenda for Eurotox. The group has proposed scientific sessions for Rhodes 2008, and Dresden 2009, and takes an active role in helping to organise the Eurotox meetings. The Molecular Toxicology group has also helped to support additional training exercises, and looks forward to developing short themed conferences.
MINUTES
Minute of Bussiness Meeting Meeting 2009 held at the EUROTOX Congress in Dresden/Germany and Annual report of activites.
Agenda and Minute of the Business Meeting 2008 held at the EUROTOX congress site, Rhodos/Greece
Chairman:
Dr Jean Lou Dorne
Toxicologist
Unit on Contaminants in the Food chain
European Food Safety Authority
Largo N. Palli 5/A
I-43100 Parma
Email:jean-lou.dorne@efsa.europa.eu
www: http://www.efsa.europa.eu